Trulance® Safety Adult patients with CIC and IBS-C. ISI remains fixed below.

Pipeline candidate

Dolcanatide for ulcerative colitis

An investigational GC-C agonist reflecting Synergy’s continued investment in GI innovation.

Development focus

Advancing a targeted approach

Research study

Dolcanatide leverages the same GC-C agonist principles as TRULANCE® with a focus on ulcerative colitis. The program emphasizes robust clinical design, transparent safety monitoring, and alignment with regulatory guidance.

  • Designed for inflammatory bowel disease populations
  • Guided by learnings from TRULANCE clinical development
  • Supports Synergy’s GI-focused pipeline strategy
See full pipeline →
Investigational status: Dolcanatide is not approved. Information is intended for awareness of Synergy’s research focus. Refer to TRULANCE for currently approved therapy details and Important Safety Information below.