Trulance® Safety Adult patients only. See Important Safety Information below.

Patient Resources

Guidance for living with CIC or IBS-C

Learn how TRULANCE® (plecanatide) is used to treat adult patients with chronic idiopathic constipation and IBS-C, and explore support to stay on therapy safely.

Getting started

Your TRULANCE care path

Work with your healthcare professional to confirm the diagnosis, review the Important Safety Information, and understand how to take TRULANCE exactly as prescribed.

1. Talk with your clinician

Discuss symptoms, prior treatments, and any medical conditions. TRULANCE is for adults only. Let your provider know about any signs of GI obstruction.

2. Review dosing & expectations

Take TRULANCE exactly as prescribed. Read the Important Safety Information; the most common side effect is diarrhea. Severe diarrhea requires contacting your healthcare provider.

3. Stay connected

Use patient support tools, coverage guidance, and lifestyle tips to stay on therapy. Reach out to your healthcare team if symptoms change.

Tools & resources

Everything patients and caregivers need in one place

Condition education

Plain-language explanations of CIC and IBS-C, symptom trackers, and questions to bring to your healthcare professional.

  • Learn about hydration, fiber, and activity guidance
  • Understand how GC-C agonists work
  • Glossary for medical terminology
Visit disease education →

Coverage & assistance

Find co-pay assistance information, insurance checklists, and reimbursement support contacts.

  • Coverage verification steps
  • What to expect from co-pay programs
  • Contact options for billing or pharmacy questions
Go to support programs →
Patients receiving support

Safety reminders

Stay informed while on therapy

  • TRULANCE is for adult patients with CIC or IBS-C; it is not for pediatric patients.
  • If severe diarrhea occurs, stop taking TRULANCE and contact your healthcare professional.
  • Keep the Important Safety Information accessible; ISI remains visible on every page.
Questions today? Call +1 (276) 248-2886 or speak with your healthcare provider for medical advice. For emergencies, contact local emergency services immediately.